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FLUID MOSAIC MODEL OF PLASMA MEMBRANE
1. It is the most acceptable model till date.
2. It was given by singer and nicolson in 1972.
3. Plasma membrane does not have uniform deposition of lipids and proteins.
4. Plasma membrane is not solid but semifluid. Nonpolar ends of phospholipids contain fatty acids which provides fluidity. Semifluid nature of lipids enable lateral movement of protein. The Semifluid nature of membrane is also important for cell growth, secretions, cell division, endocytosis, exocytosis and formation of intercellular junctions.
5. Plasma membrane is dynamic in nature due to transport ability, quick repair and ability to expand and contract.
6. In this model, proteins have been compared to icebergs floating in the sea of phospholipid bilayer.
7. At some place extrinsic protein and lipid of external surface of plasma membrane bears oligosaccharides forming glycoprotein and glycolipid. Glycoprotein and glycolipid costitute glycocalyx.
8. Glycocalyx present towards the extracellular side only.
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