Thursday 14 December 2017

CHEMICAL COMPOSITION OF PLASMA MEMBRANE

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                          CELL MEMBRANE

It is the outermost layer of an animal cell and second outermost layer of plant cell.

It was also called cytoplasmic membrane, plasmalemma.

The term cell membrane first coined by C.Nageli.

CHEMICAL COMPOSITION :- it is made up of mainly lipid, protein, carbohydrate, and some enzymes.

1) LIPID:- phospholipids, sphingolipids, glycolipids and sterols are present in cell membrane.

                        Phospholipids are two types:- 

I) Acidic(20%) - Example sphingomyelin.

II) Neutral (80%)- Example  phosphotidyl choline , phosphotidyl serine.

2) PROTEIN:- There are two types of protein intrinsic protein, extrinsic protein. Both of the proteins may be ectoprotein (lying outside), endoprotein (lying inside).

3) CARBOHYDRATES:-They are present as short unbranched or branched Chains of sugars attached either to exterior ectoproteins(forming glycoproteins) or to the polar ends of phospholipids at the external surface of the plasma membrane(forming glycolipids). The 6 principle sugars:

D-galactose, D-mannose ,L-fucose, N-acetyl neuraminic acid, N-acetyl-D-glucosamine and N-acety-D-galactosamine.

SOME IMPORTANT ENZYMES OF PLASMA MEMBRANE:-
1.Acetyl phosphatase
2.Acetyl cholinesterase (Ectoenzyme of RBC)
3.Acid phosphatase
4.Adenosine triphosphate
5.Mg2+ ATPase (Endoenzyme)
6.Na+-K+ ATPase(Ectoenzyme of RBC)
7.RNAase
8.NAD-ase (Ectoenzyme of RBC)


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